Structure and Mechanism

Anastrozole is an aromatase inhibitor (AI) that works by blocking the aromatase enzyme, reducing estrogen levels by up to 80%. It also promotes the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which support testosterone production.

Primary Benefits

• Breast Cancer Treatment: Lowers estrogen levels to prevent the growth of hormone-sensitive breast cancer cells, especially effective for post-menopausal women.
• Estrogen Control in Steroid Cycles: Prevents estrogenic side effects such as gynecomastia and water retention for anabolic steroid users, reducing risks of high blood pressure linked to water retention.
• Support in Low Testosterone Plans: Can be used alongside testosterone therapy to manage estrogen levels.

Ideal Use Cases

• Cancer Treatment: Commonly prescribed at 1 mg daily for breast cancer patients until remission, after which Nolvadex may be used as a preventative.
• Steroid Cycles: For managing estrogen levels in cycles with aromatizing steroids, like testosterone or Dianabol.
• PCT and Testosterone Therapy: While helpful in reducing estrogen during cycles, it is generally less suitable for Post Cycle Therapy (PCT) due to its strong estrogen suppression, which can interfere with bodily functions.

Dosage and Administration

• Breast Cancer: Standard dosage is 1 mg per day.
• Steroid Users: Typically, 0.5-1 mg every other day suffices; 1 mg daily may be used for short periods in competitive bodybuilding for a leaner look. Lower doses may work well with testosterone therapy.

For those using Anastrozole in steroid cycles, a healthy lifestyle, omega-3-rich diet, and regular cardiovascular exercise are essential to offset potential cholesterol issues.