1. Cosmetic Applications (e.g., wrinkle reduction)

• Forehead Lines:
  • Male and Female: 10–30 IU (divided across 4–5 injection sites).
  • Males often require higher doses due to stronger muscles.
• Glabellar Lines (Frown Lines):
  • Male and Female: 20–30 IU (divided across 5 injection sites).
• Crow’s Feet:
  • Male and Female: 6–12 IU per side (3 injection sites per side).
• Bunny Lines (Nose):
  • Male and Female: 4–10 IU (divided across 2–4 injection sites).

2. Therapeutic Applications

• Hyperhidrosis (Excessive Sweating):
  • Axillary (Underarms): 50 IU per side (total 100 IU for both sides).
  • Dosage for palms or soles is similar but adjusted based on the area.
• Migraine Treatment:
  • Male and Female: Total dose: 155–195 IU, divided across 31–39 injection sites in the head and neck.
• Muscle Spasticity (e.g., Upper Limb, Lower Limb):
  • Total dose varies significantly, often ranging from 100–400 IU, depending on the size and number of muscles treated.